GENERATION OF HETEROZYGOUS (MCRII030-A-1) AND HOMOZYGOUS (MCRII030-A-2) NR2F2/COUP-TFII KNOCKOUT HUMAN IPSC LINES

Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

The NR2F2 gene encodes the transcription factor COUP-TFII, which is upregulated in embryonic mesoderm.Heterozygous variants in NR2F2 cause a display controller spectrum of congenital anomalies including cardiac and gonadal phenotypes.We generated heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2-knockout induced pluripotent stem cell

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Repeated Exposition to Mercury (II) Chloride Enhances Susceptibility to S. schenckii sensu stricto Infection in Mice

Sporotrichosis is a subcutaneous mycosis that has re-emerged in several tropical and subtropical regions over the last decades.Growing findings suggest that the interplay of host, pathogen, and environment has a determinant effect on the diversity, local distribution, and virulence of Sporothrix schenckii sensu lato, the etiologic agent.Among the e

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High-Speed and Enhanced Motion Control for a Wheeled-Legged Humanoid Robot Using a Two-Wheeled Inverted Pendulum With Roll Joint

Wheeled-legged humanoid robots combine the mobility of wheels with the versatility of legs, offering significant advantages for locomotion.This paper proposes a hierarchical control framework CHILD TOOTHBRUSH for such robots, using a two-wheeled inverted pendulum with a roll joint (TWIP-R) as a template model.The framework integrates a motion plann

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